Development of Extended Release Gastrorentive Dosages of Ibuprofen

机译：布洛芬延长释放胃肠剂量的发展

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摘要

Ibuprofen, a water insoluble non-steroidal anti-inflammatory drugs (NSAID), is used for the treatment of cold and fever. This work was aimed at the development of extended release gastroretentive dosages of ibuprofen from the excipients composed of polyvinyl alcohol-polyethylene glycol copolymer and polyvinyl alcohol.

机译：布洛芬，一种水不溶性非甾体抗炎药（NSAID），用于治疗寒冷和发烧。这项工作旨在从由聚乙烯醇 - 聚乙二醇共聚物和聚乙烯醇组成的赋形剂组成的赋形剂的扩展释放胃内剂量的开发。

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《Controlled Release Society Annual Meeting and Exposition》|2007年||共2页
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Shaukat Ali; Carlos Santos; Anisul Quadir;
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中图分类生物工程学（生物技术）;
关键词
excipient; gastroretentive dosages; drug delivery; ibuprofen; polyvinyl alcohol; polyvinyl alcohol-polyethylene glycol; grafted copolymer and kollicoat~r protect;

机译：赋形剂;胃肠剂剂量;药物递送;布洛芬;聚乙烯醇;聚乙烯醇 - 聚乙二醇;接枝共聚物和Kollicoat〜R保护;

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1. Development and evaluation of a multiple-unit oral sustained release dosage form for S(+)-ibuprofen: preparation and release kinetics. [J] . Cox PJ, Khan KA, Munday DL, International Journal of Pharmaceutics . 1999,第1期

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2. Single- and multiple-dose pharmacokinetics of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) compared with immediate-release hydrocodone bitartrate/ibuprofen and immediate-release tramadol HCl/acetaminophen [J] . Krishna Devarakonda, Kenneth Kostenbader, Michael J Giuliani, Journal of Pain Research . 2015,第6期

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3. Adherence and persistence with single-dosage form extended-release niacin/lovastatin compared with statins alone or in combination with extended-release niacin. [J] . LaFleur J, Thompson CJ, Joish VN, The annals of pharmacotherapy . 2006,第7a8期

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4. Development of Extended Release Gastrorentive Dosages of Ibuprofen [C] . Shaukat Ali, Carlos Santos, Anisul Quadir Controlled Release Society Annual Meeting and Exposition . 2007

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5. Development of a controlled release ibuprofen by spheroidization and ethyl cellulose coating by fluidized bed process [D] . Patel, Bhaumik T. 2009

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Development of Extended Release Gastrorentive Dosages of Ibuprofen

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