THERMORESPONSIVE POLYMER CARRIER FOR TEMPERATURE-CONTROLLABLE GENE DELIVERY SYSTEM, CORRELATION IN THERMAL RESPONSE BETWEEN INTERACTION WITH DNA AND TRANSFECTION EFFICIENCY

机译：温度可控制的基因传递系统的热敏性聚合物载体，与DNA相互作用和翻译效率之间的热响应相关

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Thermoresponsive polymers having poly(N-isopropylacrylamide) unit were applied as DNA carriers for the temperature-controllable gene delivery system, which will make possible the time and site specific gene expression. Interactions between these polymer carriers and DNA were investigated by the EtBr intercalation assay. Correlation between the affinity to DNA and the transfection efficiency of polymer carriers were discussed.

机译：具有聚（N-异丙基丙烯酰胺）单元的热敏性聚合物被用作温度可控制的基因递送系统的DNA载体，这将使得时间和位点特异性基因表达成为可能。这些聚合物载体与DNA之间的相互作用通过EtBr嵌入测定法进行了研究。讨论了对DNA的亲和力与聚合物载体转染效率之间的相关性。

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《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.860-861|共2页
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Naoya Takeda; Masayuki Yokoyama; Teruo Okano;
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中图分类化学工业;
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thermosensitive polymers; gene delivery;

机译：热敏聚合物;基因传递;

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1. An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems [J] . van der Aa MAEA, Koning GA, dOliveira C, The journal of gene medicine . 2005,第2期

机译：与线性DNA共价连接的NLS肽不能提高基于阳离子聚合物的基因递送系统的转染效率
2. Thermoresponsive polymers as gene delivery vectors: Cell viability, DNA transport and transfection studies [J] . Twaites BR, Alarcon CDH, Lavigne M, Journal of Controlled Release: Official Journal of the Controlled Release Society . 2005,第2a3期

机译：热响应聚合物作为基因传递载体：细胞活力，DNA转运和转染研究
3. Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems [J] . Amin Amani, Toraj Khabiri, Samira Shafiee, Iranian Journal of Pharmaceutical Research . 2019,第1期

机译：PLA-PEG-PLA / PEI / DNA纳米粒子的制备和表征，用于提高转染效率和基因传递系统中DNA的控制释放
4. THERMORESPONSIVE POLYMER CARRIER FOR TEMPERATURE-CONTROLLABLE GENE DELIVERY SYSTEM, CORRELATION IN THERMAL RESPONSE BETWEEN INTERACTION WITH DNA AND TRANSFECTION EFFICIENCY [C] . Naoya Takeda, Masayuki Yokoyama, Teruo Okano Annual meeting of the Controlled Release Society . 2002

机译：热响应性聚合物载体用于温度可控基因递送系统，与DNA和转染效率相互作用的热响应相关性
5. Multifunctional mesoporous silica nanospheres for biosensor, stimuli-responsive controlled-release drug delivery carriers and gene transfection vectors. [D] . Lai, Cheng-Yu. 2004

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6. Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems [O] . Amin Amani, Toraj Kabiri, Samira Shafiee, 2019

机译：PLA-PEG-PLA / PEI / DNA纳米粒子的制备和表征以提高转染效率和基因传递系统中DNA的控制释放
7. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies [O] . Ruponen Marika, Ylä-Herttuala Seppo, Urtti Arto 1999

机译：聚合物和脂质体基因递送系统与细胞外糖胺聚糖的相互作用：物理化学和转染研究

THERMORESPONSIVE POLYMER CARRIER FOR TEMPERATURE-CONTROLLABLE GENE DELIVERY SYSTEM, CORRELATION IN THERMAL RESPONSE BETWEEN INTERACTION WITH DNA AND TRANSFECTION EFFICIENCY

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