ENHANCED SKIN PENETRATION OF ASCORBYL PALMITATE BY LIPOGEL FORMULATION AND CATHODAL IONTOPHORESIS

摘要

Ascorbyl palmitate(AsP), a lipophilic prodrug of ascorbic acid(AsA), was formulated as lipogel systems consisting either neutral or negatively charged liposomes. Its skin penetration was enhanced by cathodal iontophoresis.