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Development of a New Vascular Endoscopic System for Observing Inner Wall of Aorta Using Intermittent Saline Jet

机译:间歇性盐水射流观察主动脉内壁的新型血管内窥镜系统的研制

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A prototype endoscopic system for observing inner wall of aorta was developed and tested in vivo using swine. The purpose of this system is to visualize the inner wall of aorta without stopping aortic flow for the use of an assistive technique for endovascular interventions such as stent-graft placement for aortic aneurysm. The technique newly introduced for this purpose was the use of intermittent high-pressure saline jet synchronized to heart beat (diastolic phase). For preliminary studies, a commercially available broncho-scope having an outer diameter of 5mm with a biopsy channel was used, and a discharging system for intermittent high-pressure saline jet was constructed using a high-speed solenoid valve and a pressurizing tank. From in vitro tests, it was confirmed that we could obtain sufficient amount of saline jet (about lml) within short period of time (about 100 ms) with the driving pressure of 0.1 MPa. Based on these results, we conducted in vivo tests using swine with the body weight of about 30 kg. The tip of the endoscope was introduced from the abdominal aorta and inserted proximally about 30 cm. At this point, the saline jet was discharged (period: 200 ms, driving pressure: 0.2 MPa), and then we could clearly observe the aortic bifurcations during the flushing period. This result strongly suggests an availability of the present method as an assistive technology for the endovascular interventions in aorta.
机译:开发了用于观察主动脉内壁的原型内窥镜系统,并使用猪在体内进行了测试。该系统的目的是在不停止主动脉血流的情况下可视化主动脉内壁,以使用辅助技术进行血管内干预,例如用于主动脉瘤的覆膜支架置入术。为此目的新引入的技术是使用与心跳(舒张期)同步的间歇性高压盐水喷射。为了进行初步研究,使用了具有活检通道,外径为5mm的市售支气管镜,并使用高速电磁阀和加压罐构建了间歇高压盐水喷射的排放系统。通过体外试验,证实了在0.1 MPa的驱动压力下,我们可以在短时间内(约100毫秒)获得足够量的盐水喷射(约1毫升)。根据这些结果,我们使用体重约30公斤的猪进行了体内测试。从腹主动脉插入内窥镜的尖端,并向近端插入约30 cm。此时,盐水喷射被排出(时间:200 ms,驱动压力:0.2 MPa),然后我们可以清楚地看到冲洗期间的主动脉分叉。该结果强烈暗示了本方法作为用于主动脉的血管内介入的辅助技术的可用性。

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