Applications of micro-systems technology for characterization and detection of microorganisms

摘要

Biological entities such as microorganisms are exquisite systems that have many intricate properties and can perform complex functions. We present the use of electrical characterization to examine two properties and functions of the microorganisms within novel micro-systems. One system takes advantage of the charge state of the cells to measure their electrophoretic mobility through micro-pores. The second system measures impedance changes produced by the metabolic activity of cells to determine their viability. Such devices with an electronic signal output can be very useful in producing practical systems for rapid detection and characterization of cells for a wide variety of applications in the food and health industries.