GLATIRAMER ACETATE ANALYSIS IN THE MUCOSA OF THE RAT INTESTINE

机译：大鼠肠粘膜中的格拉默乙酸盐分析

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Glatiramer acetate (GA) introduced into sacs of the rat intestine was detected in intestinal wall fractions. In intestinal segments without luminal contents GA degraded faster in proximal regions compared with the colon. Fecal meter caused rapid degradation of GA in the colon.

机译：在肠壁部分中检测到引入大鼠肠囊的醋酸格拉替雷（GA）。与结肠相比，在无腔含量的肠段中，GA在近端区域的降解速度更快。粪便计导致结肠中GA的快速降解。

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来源
《International symposium on controlled release of bioactive materials;Consumer diversified products conference》|2001年|p.866-867|共2页
会议地点 San Diego CA(US);San Diego CA(US)
作者
S. Haupt; E. Gi; R. Tirosh; E. Klinger; A. Gad; A. Rubinstein;
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The Hebrew University of Jerusalem School of Pharmacy P.O.Box 12065 Jerusalem 91120 Israel;

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关键词
peptide drugs; oral drug delivery; mucosa uptake; intestinal proteolysis; colon; small intestine; rat;

机译：肽类药物；口服药物递送；粘膜摄取肠蛋白水解;结肠;小肠;鼠;

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GLATIRAMER ACETATE ANALYSIS IN THE MUCOSA OF THE RAT INTESTINE

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