Functional genomic analysis of Deinococcus radiodurans resistance to ionizing radiation

摘要

Deinococcus radiodurans R1 is a remarkable bacterium for its extreme resistance to ionizing radiation. To define the repertoire of D. radiodurans genes responding to acute ionizing irradiation, transcrip-tome dynamics were examined in the recovering irradiated cells. The expression patterns of the majority of the induced genes resembled that of recA that showed up-regulation in the early phase and down-regulation in the late phase. The RecA-liks induced genes include those involved in DNA metabolism, cell envelope formation, cellular transport, and transcription and translation process.