Surface-Modified Lipid Nanoparticles For a Selective Parenteral Delivery of Paclitaxel

机译：表面修饰的脂质纳米颗粒用于紫杉醇的选择性肠胃外给药。

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Paclitaxel loaded lipid nanosuspension surfacemodifiedrnwith galactose moiety was prepared by hotrnmelt homogenization. The pharmacokinetic behaviorrnand liver targeting were evaluated in rats afterrnintravenous (iv) administration.

机译：通过热熔均质化制备了用半乳糖部分表面修饰的负载紫杉醇的脂质纳米悬浮液。在静脉内（iv）给药后，在大鼠中评估了药代动力学行为和肝靶向。

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来源
《Controlled Release Society 31st annual meeting transactions: abstracts》|2004年|1-2|共2页
会议地点 Honolulu HI(US)
作者
Sung-Up Choi; Sun-Kyu Kim; Mi-Kyoung Yoon; Young Wook Choi;
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作者单位

College of Pharmacy, Chung-Ang University, Seoul 156-756, KOREArnyurane@hanmail.net;

College of Pharmacy, Chung-Ang University, Seoul 156-756, KOREA;

College of Pharmacy, Chung-Ang University, Seoul 156-756, KOREA;

College of Pharmacy, Chung-Ang University, Seoul 156-756, KOREA ywchoi@cau.ac.kr;

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原文格式 PDF
正文语种 eng
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关键词
paclitaxel; surface-modification; rngalactose moiety; lipid nanoparticles; liver targeting;

机译：紫杉醇表面修饰半乳糖部分脂质纳米颗粒；肝靶向;

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专利

1. Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases [J] . Palanivel Ganesan, Prakash Ramalingam, Govindarajan Karthivashan, International Journal of Nanomedicine . 2018,第6期

机译：固体脂质纳米颗粒和表面修饰的固体脂质纳米颗粒递送系统在各种慢性疾病中口服递送植物生物活性化合物的最新进展
2. Development and evaluation of lipid nanoparticles for paclitaxel delivery: a comparison between solid lipid nanoparticles and nanostructured lipid carriers [J] . Wenting Xu, Mi-Kyung Lee Journal of pharmaceutical investigation . 2016,第7期

机译：紫杉醇脂质纳米粒的开发和评估：固体脂质纳米粒与纳米结构脂质载体的比较
3. Development and evaluation of lipid nanoparticles for paclitaxel delivery: a comparison between solid lipid nanoparticles and nanostructured lipid carriers [J] . Wenting Xu, Mi-Kyung Lee Journal of pharmaceutical investigation . 2015,第7期

机译：紫杉醇递送脂质纳米粒子的开发和评价：固体脂质纳米粒子与纳米结构脂质载体的比较
4. Surface-Modified Lipid Nanoparticles For a Selective Parenteral Delivery of Paclitaxel [C] . Controlled Release Society annual meeting . 2004

机译：用于选择性肠胃外递送紫杉醇的表面改性脂质纳米颗粒
5. Development and Characterization of LDV Peptide Targeted Nanocarriers for Paclitaxel Delivery: A Comparative Study of Micelles, Liposomes and Solid Lipid Nanoparticles [D] . Dattani, Poonam. 2019

机译：紫杉醇传递的LDV肽靶向纳米载体的开发和表征：胶束，脂质体和固体脂质纳米颗粒的比较研究。
6. Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases [O] . Palanivel Ganesan, Prakash Ramalingam, Govindarajan Karthivashan, 2018

机译：固体脂质纳米颗粒和表面修饰的固体脂质纳米颗粒输送系统在各种慢性疾病中口服输送植物生物活性化合物的最新进展
7. Co-delivery of paclitaxel and tanespimycin in lipid nanoparticles enhanced anti-gastric-tumor effect in vitro and in vivo [O] . Liang Ma, Dawei Yang, Zhaoxin Li, 2018

机译：在脂质纳米粒子中的紫杉醇和TaneSpimycin的共同递送增强了体外和体内的抗胃肿瘤作用

Surface-Modified Lipid Nanoparticles For a Selective Parenteral Delivery of Paclitaxel

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