Dose Proportional Pharmacokinetics of a Methylphenidate Extended-Release Capsule Formulation

机译：哌醋甲酯延长释放胶囊制剂的剂量比例药代动力学

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The objective of this work was to assess the dosernproportionality of different strengths of arnmethylphenidate (MPH) extended release (ER)rncapsule formulation in healthy adults.

机译：这项工作的目的是评估健康成年人中不同强度的哌醋丙酯（MPH）缓释（ER）胶囊制剂的剂量比例性。

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来源
《Controlled Release Society 31st annual meeting transactions: abstracts》|2004年|1-2|共2页
会议地点 Honolulu HI(US)
作者
M. Rochdi; M. A. González; K. Smith; S. J. Hirshey Dirksen;
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GloboMax? Division of ICON plc, Hanover, MD 21076 rochdim@iconus.com tel:410-782-2741;

P'Kinetics International, Inc.Pembroke Pines, FL 33027;

Celltech Americas, Inc. Rochester, NY 14603;

Celltech Americas, Inc. Rochester, NY 14603;

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1. Dose-proportional pharmacokinetics of a methylphenidate extended-release capsule. [J] . Rochdi M, Gonzalez MA, Dirksen SJ International journal of clinical pharmacology and therapeutics . 2004,第5期

机译：哌醋甲酯缓释胶囊的剂量比例药代动力学。
2. Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate: Evaluation of Dose Proportionality, Food Effect, Multiple-Dose Modeling, and Comparative Bioavailability with Immediate-Release Methylphenidate in Healthy Adults [J] . Liu Tao, Gobburu Jogarao V. S., Po Michelle D., Journal of child and adolescent psychopharmacology . 2019,第3期

机译：HLD200的药代动力学，延迟释放和延长释放甲基苯胺：对剂量比例，食物效应，多剂量建模和对健康成年人的即时释放甲基酚的比较生物利用度评估
3. Single-Dose Pharmacokinetics of Methylphenidate Extended-Release Multiple Layer Beads Administered as Intact Capsule or Sprinkles Versus Methylphenidate Immediate-Release Tablets (Ritalin((R))) in Healthy Adult Volunteers [J] . Adjei Akwete, Teuscher Nathan S., Kupper Robert J., Journal of child and adolescent psychopharmacology . 2014,第10期

机译：在健康成人志愿者中以完整胶囊形式给药或喷洒哌醋甲酯速释片（Ritalin（R））的哌醋甲酯延长释放多层珠的单剂量药代动力学
4. Dose Proportional Pharmacokinetics of a Methylphenidate Extended-Release Capsule Formulation [C] . Controlled Release Society annual meeting . 2004

机译：甲基酚盐延长释放胶囊配方的剂量比例药代动力学
5. Development of novel spray coated soft elastic gelatin capsule sustained release formulations of nifedipine, bioavailability and bioequivalence of verapamil HCL controlled release formulations, pharmacokinetics of terbinafine after single oral doses in raptors. [D] . Fahmy, Sahar Abd El-Sattar. 2004

机译：硝苯地平新型喷雾包衣的软弹性明胶胶囊缓释制剂的开发，维拉帕米盐酸盐控释制剂的生物利用度和生物等效性，在猛禽中单次口服剂量后特比萘芬的药代动力学。
6. Pharmacokinetics of HLD200 a Delayed-Release and Extended-Release Methylphenidate: Evaluation of Dose Proportionality Food Effect Multiple-Dose Modeling and Comparative Bioavailability with Immediate-Release Methylphenidate in Healthy Adults [O] . Tao Liu, Jogarao V.S. Gobburu, Michelle D. Po, -1

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7. Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate: Evaluation of Dose Proportionality, Food Effect, Multiple-Dose Modeling, and Comparative Bioavailability with Immediate-Release Methylphenidate in Healthy Adults [O] . Tao Liu, Jogarao V.S. Gobburu, Michelle D. Po, 2019

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8. Pharmacokinetics, Bioavailability, and Dose Range-Finding of NSC-D629243 in Beagle Dogs (Phase 1) and Bioavailability of NSC-D62924 in Various Formulations in Beagle Dogs (Phase 2). [R] . Freeman, G. B., Tosca, P. J., Placke, M. E. 1991

机译：比格犬中的NsC-D629243（阶段1）的药代动力学，生物利用度和剂量范围 - 发现以及比格犬中各种制剂中NsC-D62924的生物利用度（阶段2）。

Dose Proportional Pharmacokinetics of a Methylphenidate Extended-Release Capsule Formulation

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