The formulation of composite capsule, hard, fixed dose formulation of composite and preparation method of the composite hard capsule formulation of

摘要

One aspect of the present invention provides a complex of hard capsule and a preparation method thereof, in which the complex of hard capsule comprising.In a separate state: a separate part of dutasterida dutasterida or a pharmacologically acceptable salt comprising the same; and a separate part of tamsulosin including tansulosinOr a pharmacologically acceptable salt thereof, in which the part independent of dutasterida is a preparation containing an emulsion autoemulsificante which consists of dutasterida,An oil and a surfactant; a separate part of tamsulosin is a solid preparation containing a release agent prolonged; and the part of dutasterida independent and separate part of tansulOsina are included in a separate state and can be inserted into capsules, 0 to 3.