Mycobacterium tuberculosis infection present future: Diagnosis, Prevention and treatment

摘要

Tuberculosis has long been one of the most important infectious diseases in human beings. The incidence of tuberculosis has been decreasing since World War II, but it is still a difficult-to-control epidemic disease in the world. Further recently, since 1980 ages, the incidence rate of tuberculosis has been again increasing and re-emerging not only in the developing countries, but also in the developed ones, due to HIV co-infection, over-crowded population, frequent dislocaiton, homelesses and poverty (Fig.1 and 2). although tuberculosis has long history in host-parasite relationship for human, however, the mechanism of the infection, the immunological responses, the diagnostic tool and protective vaccine development should be further investigated. In this context, I would like to point out the present problems of each subjected in tuberculous (tB) infection.