Use of an amino acid sequence derived from Mycobacterium tuberculosis or its corresponding nucleic acid for diagnosis and prevention of Mycobacterium tuberculosis infection, and a diagnostic kit and vaccine derived therefrom

摘要

The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.