SMALL MOLECULE INHIBITOR FOR TARGETED INHIBITION OF PITPNM3 AND APPLICATION THEREOF

摘要

11 small molecule inhibitors having the biological effects of targeted inhibition of the PITPNM3-mediated cell adhesion and the biological effects of targeted inhibition of the CCL18-PITPNM3-mediated cell migration and adhesion, can inhibit various types of tumor metastases mediated by PITPNM3 activation such as breast cancer, hepatocellular carcinoma, pancreatic ductal cancer, and lung cancer, and have wide application range and strong targeting.