Performance monitoring of topical citrate anticoagulation

摘要

The monitoring device provides local citrate anticoagulation therapy (RCA) in a blood treatment system configured to administer citrate to an extracorporeal blood circuit (10) upstream of a dialyzer (11) during a treatment period. It works like monitoring. At successive time steps during the treatment period, the monitoring device obtains current measurements of systemic ionized calcium (iCaSYS) or systemic total calcium (CaSYS), downstream of the dialyzer (11) in the extracorporeal blood circuit (10). Or run a predetermined algorithm on the current measurement to generate a current calculated value representing the ionized calcium (iCa2, iCa3) in the blood at a selected location (loc2, loc3) upstream, local Present and/or evaluate current calculated values for evaluation of citrate anticoagulation therapy. The need for conventional blood sampling and blood analysis upstream and/or downstream of the dialyzer, eg during CRRT, is thereby significantly reduced.