首页> 外国专利> METHOD FOR THE TREATMENT OF UNCOMPLICATED NECROTIZING ENTEROCOLITIS IN NEWBORNS WITH A BACTERIAL INFECTION AND IF INTRAUTERINE INFECTION IS SUSPECTED

METHOD FOR THE TREATMENT OF UNCOMPLICATED NECROTIZING ENTEROCOLITIS IN NEWBORNS WITH A BACTERIAL INFECTION AND IF INTRAUTERINE INFECTION IS SUSPECTED

机译:患有细菌感染且怀疑宫内感染的新生儿无并发症坏死性小肠结肠炎的治疗方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to therapy and gastroenterology, and can be used in complex treatment for uncomplicated necrotizing enterocolitis (NEC) in newborns with a bacterial infection and if intrauterine infection is suspected. To do this, determine the value of C-reactive protein and pathogenic agents. When the value of C-reactive protein is >12 mg/l, the bacteriophage, selected taking into account the pathogen in the gastrointestinal tract, is injected into the stomach through a nasogastric tube, 5 ml 2 times a day with an exposure of 30 minutes, and a mixture of 5 ml of this bacteriophage with a solution of Metrogyl 7, 5 mg/kg heated to 37.2°C is administered rectally through a gas outlet tube according to the principle of high enemas with an exposure of 30 minutes 3 times a day for 10 days.;EFFECT: invention provides increased efficiency of treatment without the use of antibiotics, selective effect on pathogenic pathogens without suppression of the normal flora of the gastrointestinal tract, exclusion of the toxic effects of antibiotics, activation of the immune response.;1 cl, 2 ex
机译:领域:医学。;物质:本发明涉及药物,即治疗和胃肠病学,可用于患有细菌感染的新生儿的无并发症坏死性小肠结肠炎(NEC)的复杂治疗,如果怀疑宫内感染。为此,确定C反应蛋白和病原体的价值。当C-反应蛋白的值>12 mg/l时,考虑到胃肠道中的病原体选择的噬菌体通过鼻胃管注射到胃中,每天2次,每次5 ml,暴露30分钟,以及5 ml该噬菌体与Metrogyl 7溶液的混合物,根据高位灌肠的原则,加热至37.2°C的5 mg/kg通过排气管直肠给药,每天3次,每次30分钟,持续10天。;作用:本发明在不使用抗生素的情况下提高治疗效率,在不抑制胃肠道正常菌群的情况下对病原体产生选择性作用,排除抗生素的毒性作用,激活免疫反应。;1 cl,2 ex

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