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Antibodies targeting galactan based o antigens in creubea neutrinae

机译:抗体靶向甲酰胺基甲酰酸酯的抗原中华关系

摘要

The present invention relates to a lipopolysaccharide (LPS) O of Klebsiella pneumoniae in which the epitope is encapsulated in a galactan-III repeat unit, the galactan-III repeat unit being a branched galactose homopolymer of formula (I). An isolated antibody that specifically recognizes a galactan-III epitope of an antigen construct is provided. The present invention further provides a pharmaceutical preparation or a diagnostic preparation containing the antibody, and a method for producing the antibody. [Selection figure] None
机译:本发明涉及Klebsiella肺炎的脂多糖(LPS)O,其中表位被包封在半乳糖-III重复单元中,所述吡喃-III重复单元是式(I)的支链半乳糖均聚物。 提供了专门识别抗原构建体的半乳糖-III表位的分离的抗体。 本发明进一步提供了含有抗体的药物制剂或诊断制剂,以及制备抗体的方法。 [选择图]没有

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