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ANTIBODIES TARGETED TO O-ANTIGEN BASED ON GALACTAN FROM K. PNEUMONIAE

机译:靶向基于K.Pnneumoniae的半乳糖的O-抗原的抗体

摘要

The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of Klebsiella pneumoniae, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galactose homopolymer of Formula (I). The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody.
机译:本发明提供了分离的抗体,其特异性地识别脂多糖(LPS)抗原结构的吡喃乳糖(LPS)O-抗原结构的乳酸乳粥,该表位掺入吡酰基-III重复单元中,其中半乳糖-III重复单元是分支的 式(I)的半乳糖均聚物。 本发明还提供了包含所述抗体的药物或诊断制剂,以及产生所述抗体的方法。

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