首页> 外国专利> A Biosensor for Diagnosis of Myocardial Infarction Using Electrochemical And Localized Surface Plasmon Resonance Dual-Detection Method And A Diagnostic Method Using The Same

A Biosensor for Diagnosis of Myocardial Infarction Using Electrochemical And Localized Surface Plasmon Resonance Dual-Detection Method And A Diagnostic Method Using The Same

机译:一种使用电化学和局部等离子体共振双检测方法和使用相同诊断方法的心肌梗死的生物传感器

摘要

The present disclosure relates to a substrate unit capable of transmitting visible light and ultraviolet light and transmitting electricity; Nanoparticles in which nanoparticles are deposited on the substrate; and a binding portion comprising a plurality of multifunctional DNA structures including a three-way junction that binds to the nanoparticle portion and specifically binds to myocardial troponin I (cTnI); Myocardial infarction, characterized in that when the multifunctional DNA construct is combined with the myocardial troponin I (CTnI), the optical properties according to electrical impedance and local surface plasmon resonance (LSPR) are changed. It relates to a biosensor for diagnosis and a diagnosis method therefor.
机译:本公开涉及一种基板单元,其能够传递可见光和紫外线和传递电力; 其中纳米颗粒沉积在基材上的纳米颗粒; 和结合部分,其包含多官能DNA结构,包括与纳米颗粒部分结合的三通结,并且特异性结合心肌肌钙蛋白I(CTNI); 心肌梗死,其特征在于,当多功能DNA构建体与心肌肌钙蛋白I(CTNI)结合时,改变根据电阻抗和局部表面等离子体共振(LSPR)的光学性质。 它涉及一种用于诊断和诊断方法的生物传感器。

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