Heterocyclic derivatives used as Nav1.7 and Nav1.8 blockers

摘要

The present invention relates to a heterocyclic derivative having blocking activity of translocation-opening sodium channels such as Nav1.7 and Nav1.8 channels, and useful for the treatment or prevention of translocation-opening sodium channel-related diseases and disorders. The present invention also relates to a pharmaceutical composition comprising the compound, and the use of the compound and composition for the prevention or treatment of a dislocation-apparent sodium channel-related disease.