Method for producing Salvia phosphoric acid a using recombinant Escherichia coli and recombinant Escherichia coli

摘要

Gene recombination bacteriaThe fungusα－ Hydroxycarboxylic acid dehydrogenaseL-amino acid oxidaseExogenous L-glutamate dehydrogenaseExogenous L-lactate dehydrogenaseAlternatively, any one selected from the group consisting of a co expression combination of glucose dehydrogenase and tyrosine phenol lyase is coexpressed andGenes associated with degradation of phenolic compounds are knocked out.The recombinant bacterium can be used for the production of optically pure 3 - (3,4-dihydroxyphenyl) - 2-hydroxypropionic acid.Further, a method for producing Salvia phosphoric acid a using the recombinant bacterium is provided.No selection