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Methods of providing solriamfetol therapy to subjects with impaired renal function
Methods of providing solriamfetol therapy to subjects with impaired renal function
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机译:向受损肾功能受损的受试者提供Solriamfetol疗法的方法
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摘要
The invention relates to methods for decreasing adverse effects associated with solriamfetol ([R]-2-amino-3-phenylpropylcarbamate) therapy in subjects with impaired renal function. In particular, the invention provides an optimized dose escalation scheme for subjects with moderate renal impairment which results in the subjects having increased tolerance to adverse effects associated with the administration of solriamfetol. The invention also provides adjusted dosing for safe therapeutic use of solriamfetol in subjects having severe renal impairment.
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