SYNTHETIC PEPTIDE MIMICS OF THE L1 PROTEIN OF HPV, HPV DIAGNOSIS METHOD, HPV DIAGNOSIS SYSTEM, PHARMACEUTICAL COMPOSITION AND USE THEREOF IN THE TREATMENT OR PREVENTION OF HPV

摘要

The present invention relates to the selection and characterization of synthetic peptides designed and synthesized from analysis of mimotope phage clones of the immunological epitope of the L1 protein of the human papillomavirus (HPV) The synthesized peptides were immunoreactive and able to detect IgA antibodies in samples of bodily fluids from patients with HPV, and could be used in the diagnosis of HPV. In addition to this, said peptides were able to trigger an in vivo immune response. The present invention relates to the selection, characterization and use of these novel synthesized peptides both for diagnosing and for treating and/or preventing HPV. The present invention also describes a method for diagnosing HPV, a pharmaceutical composition and the use thereof.