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Method, uses thereof and device for analyzing an analyte using surface enhanced Raman spectroscopy
Method, uses thereof and device for analyzing an analyte using surface enhanced Raman spectroscopy
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机译:使用表面增强拉曼光谱法分析分析物的方法,用途及其用途
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摘要
A method for analysing an analyte (3) using surface enhanced Raman spectroscopy (SERS), comprising the following steps: (a) providing an essentially flat or topologically structured metal surface (1) of a SERS-active metal; (b) depositing the analyte (3) or an open pore matrix material (5) on the surface (1); (c) depositing a multitude of nano-droplets (2) of a SERS-active metal on top of the analyte (3) or the open pore matrix material (5), respectively; and (d) spectroscopically analysing, by scanning laser irradiation and using SERS, the analyte sandwiched between the surface (1) and the multitude of nano-droplets (2). The diameter of the nano-droplets (2) is in the range of 5-70 nm, and the distance between adjacent nano-droplets (2) is smaller than their diameter, and wherein step c) is carried out by PVD or by sputtering SERS-active metal.
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