SURFACE-MODIFIED EXOSOMES USING BILE ACID, METHOD FOR PRODUCING THEREOF AND METHOD FOR INDUCING PROLIFERATION OF CELLS

摘要

The present invention provides a surface-modified exosome using a bile acid, a method for producing the exosome, and a method for inducing cell proliferation using a bile acid. According to the method for inducing cell proliferation and the method for producing exosomes, cells can effectively proliferate using bile acids, and the production efficiency of exosomes can be increased, and the bile acid surface-modified exosomes have improved cartilage regeneration efficiency and biostability. can In addition, the cells proliferated according to the cell proliferation inducing method and the bile acid surface-modified exosomes can be used as a composition for tissue regeneration, and the therapeutic effect such as cartilage tissue regeneration can be further improved by using the same.