The current disclosure provides for mapping medical images to style transferred medical images using deep neural networks, while maintaining clinical quality of the style transferred medical image, thereby enabling a clinician to evaluate medical images in a preferred style without loss of clinically relevant content. In one embodiment the current disclosure provides for a method comprising, acquiring a medical image of an anatomical region of a subject, wherein the medical image is in a first style, selecting a target style, wherein the target style is distinct from the first style, selecting a clinical quality metric, selecting a trained style transfer network based on the target style and the clinical quality metric, mapping the medical image to a style transferred medical image using the trained style transfer network, wherein the style transferred medical image is in the target style, and displaying the style transferred medical image via a display device.
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