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STERILIZATION METHOD FOR DRY COLLAGEN-BASED BIOMATERIAL

机译:干胶原基生物材料的灭菌方法

摘要

The present invention provides a sterilization method for a dry collagen-based biomaterial, comprising the following steps: immersing a collagen-based biomaterial in an antibiotic solution, and then washing same, so as to obtain a primarily sterilized collagen-based biomaterial; immersing the primarily sterilized collagen-based biomaterial in a peroxyacetic acid solution, shaking same at room temperature, and then washing same, so as to obtain a secondarily sterilized collagen-based biomaterial; and immersing the secondarily sterilized collagen-based biomaterial in an organic solvent, and performing dehydration and drying after immersion, so as to obtain a dry collagen-based biomaterial. The present invention provides simple and quick operations, does not require a professional sterilization device, and effectively solves the problems that sterilization processes affect the structural stability and the usage performance, and has incomplete sterilization, difficult operations, and low production cost.
机译:本发明提供了一种用于干燥胶原基生物材料的灭菌方法,包括以下步骤:浸入抗生素溶液中​​的基于胶原基生物材料,然后洗涤相同,从而获得主要灭菌的基于胶原基生物材料;将主要灭菌的基于胶原基生物材料浸入过氧乙酸溶液中,在室温下振动,然后洗涤相同,以获得第二灭菌的基于胶原基生物材料;并浸入有机溶剂中的基于灭菌的基础胶原基生物材料,并在浸渍后进行脱水和干燥,以获得干燥的基于胶原基生物材料。本发明提供简单且快速的操作,不需要专业的灭菌装置,有效解决灭菌过程影响结构稳定性和使用性能的问题,并且具有不完全的灭菌,困难的操作和低生产成本。

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