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METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME
METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME
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机译:重新激活无效X染色体基因的方法
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摘要
Methods for reactivating genes on the inactive X chromosome that include administering an inhibitor of XIST RNA and an inhibitor of an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein.
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