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DIRECT READING DETECTION KITS FOR SURFACE CONTAMINATION BY ANTINEOPLASTIC DRUGS

机译:直接读取抗肿瘤药物表面污染的检测试剂盒

摘要

Methods, kits and devices for detecting antineoplastic drug contamination of a surface are provided according to aspects of the present invention. According to aspects of the invention, methods for detecting antineoplastic drug contamination of a surface include providing a wetting solution compatible with the antineoplastic drug and formulated to promote release of the drug from the surface to be assayed; providing a solid matrix for reversible absorption of the antineoplastic drug; contacting the solid matrix with the wetting solution, generating an assay matrix; contacting the assay matrix and the surface, generating a surface sample; contacting the surface sample with a volume of wetting solution, generating a fluid test sample; and quantifying the antineoplastic drug in the fluid test sample by lateral flow assay to produce an assay result, thereby detecting antineoplastic drug contamination of the surface.
机译:根据本发明的方面,提供了用于检测表面的抗肿瘤药物污染的方法,试剂盒和装置。根据本发明的各方面,用于检测表面抗肿瘤药物污染的方法包括提供与抗肿瘤药物相容的润湿溶液,并配制以促进药物从待测定的表面释放。提供固体基质,用于可逆吸收抗肿瘤药物;用润湿溶液接触固体基质,产生测定基质;接触测定基质和表面,产生表面样品;用体积的润湿溶液接触表面样品,产生流体测试样品;通过横向流动测定量化流体试验样品中的抗肿瘤药物以产生测定结果,从而检测表面的抗肿瘤药物污染。

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