Expression of ASC, expression of NLRP3, and / or its analogues for inhibiting the formation of NLRP3 inflammasome complex

摘要

The use of diacerein or analogs thereof provides methods and compositions for inhibiting ASC expression, NLRP3 expression, and / or NLRP3 inflammasome complex formation. Also provided are methods and compositions for treating and / or preventing diseases mediated by ASC and / or NLRP3 and / or by formation of the NLRP3 inflammasome complex by using diacerein or analogs thereof. Is done.