diacerein or analogues thereof to inhibit asc expression, nlrp3 expression and / or inflammasome nlrp3 complex formation

摘要

Methods and compositions are provided for inhibiting asc expression, nr3r3 expression and / or formation of nr3r3 inflammatory complex using diacerein or analogs thereof. Also provided are methods and compositions for the treatment and / or prevention of an asc and / or nr3r3 mediated disease and / or formation of an nRr33 inflammasome complex using diacerein or analogs thereof.