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IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation

机译：IAPP /淀粉蛋白沉积与朗格汉斯胰岛β细胞中ASC和IL-1β的表达相关，直接引发NLRP3炎症组活化

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Shinnosuke Morikawa; Naoe Kaneko; Chikara Okumura; Haruka Taguchi; Mie Kurata; Toshihiro Yamamoto; Haruhiko Osawa; Ayaka Nakanishi; Tamotsu Zako; Junya Masumoto;
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1. IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation [J] . Shinnosuke Morikawa, Naoe Kaneko, Chikara Okumura, International journal of immunopathology and pharmacology. . 2018,第1期

机译：IAPP /淀粉样蛋白沉积与朗格汉斯胰岛β细胞中ASC和IL-1β的表达有关，直接引发NLRP3炎症小体活化
2. Deoxynivalenol enhances IL-1? expression in BV2 microglial cells through activation of the NF-κB pathway and the ASC/NLRP3 inflammasome [J] . Ilandarage Menu Neelaka Molagoda, Seunghun Lee, Rajapaksha Gedara Prasad Tharanga Jayasooriya, EXCLI Journal . 2019,第3期

机译：脱氧性苯酚增强IL-1？通过激活NF-κB途径和ASC / NLRP3炎性的BV2微胶质细胞中的表达
3. Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis [J] . I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Scientific reports. . 2016,第1期

机译：Pyk2通过直接磷酸化ASC激活NLRP3炎性炎症，并有助于抑制炎症凋亡的腹膜炎
4. Lysosomal destabilization in retinal pigment epithelial cells activates the NLRP3 inflammasome and induces IL-1beta secretion. [D] . Tseng, Wen Allen. 2014

机译：视网膜色素上皮细胞中的溶酶体去稳定化激活NLRP3炎性小体并诱导IL-1β分泌。
5. IAPP/amylin deposition which is correlated with expressions of ASCand IL-1β in β-cells of Langerhans’ islets directly initiates NLRP3inflammasome activation [O] . Shinnosuke Morikawa, Naoe Kaneko, Chikara Okumura, 2018

机译：IAPP /淀粉样蛋白沉积与ASC的表达有关Langerhans胰岛β细胞中的IL-1β和IL-1β直接引发NLRP3炎性体激活
6. Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux [O] . Mausita Karmakar, Michael Katsnelson, Hesham A. Malak, 2015

机译：肺瘤蛋白诱导的嗜中性粒细胞IL-1β处理由NLRP3 / ASC炎症组和Caspase-1激活介导，取决于K + Efflux

IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation

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