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Combination Therapy Using Anti-SSEA-4 Antibodies in Combination with Tumor Treatment

机译:使用抗SSEA-4抗体与肿瘤治疗组合的联合疗法

摘要

The present disclosure generally relates to methods and compositions of treatment comprising administering an anti-SSEA-4 antibody alone or in synergistic combination with an additive and/or other therapeutic agent in oncology to enhance therapeutic efficacy, whereby The interaction alters epitope binding of Siglec-9 proteins, including human Siglec-9 or mammalian Siglec-9, and the use of such anti-SSEA-4 compositions prevents, reduces the risk of, or prevents individuals with cancer; It relates to methods and compositions of treatment effective for treating.
机译:本公开一般涉及治疗的方法和组合物,其包括单独施用抗SSEA-4抗体或与肿瘤中的添加剂和/或其他治疗剂在肿瘤学中施用的抗SSEA-4抗体,以提高治疗效果,从而改变Siglec-的表位结合9种蛋白质,包括人类Siglec-9或哺乳动物Siglec-9,以及使用这种抗SSEA-4组合物可防止,降低风险或阻止癌症的患者;它涉及有效治疗的治疗方法和组合物。

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