A vector for transformation of Mycoplasma hypernewsonae, a strain of transformed Mycoplasma hyaminimonitors, and their use

摘要

To provide methods for engineering Mycoplasma hyopneumoniae in order to prepare transformed variant strains usable as vaccines against porcine diseases.SOLUTION: Disclosed herein is a method for preparing a mutant strain of Mycoplasma hyopneumoniae (Mhyo), comprising a step of transforming a strain of M. hyopneumoniae using a carrier vector which comprises at least one heterogenous DNA sequence under the regulation of a DNA sequence in the promoter region of M. hyopneumoniae, where the carrier vector is selected from the group consisting of replication plasmid vectors and transposon vectors.SELECTED DRAWING: None