VECTORS FOR TRANSFORMING MYCOPLASMA HYOPNEUMONIAE, TRANSFORMED MYCOPLASMA HYOPNEUMONIAE STRAINS AND THE USE THEREOF

摘要

To provide methods for engineering Mycoplasma hyopneumoniae in order to prepare transformed variant strains usable as vaccines against porcine diseases.SOLUTION: Disclosed herein is a method for preparing a mutant strain of Mycoplasma hyopneumoniae (Mhyo), comprising a step of transforming a strain of M. hyopneumoniae using a carrier vector which comprises at least one heterogenous DNA sequence under the regulation of a DNA sequence in the promoter region of M. hyopneumoniae, where the carrier vector is selected from the group consisting of replication plasmid vectors and transposon vectors.SELECTED DRAWING: None