A guide wire for minimally invasive surgery with a distal wire end piece (3, 11) adjacent a main wire piece (2), wherein the guide wire (1, 10) comprises an inner shaft (4, 14) and at least one protective layer surrounding the inner shaft (4, 14) at least at the distal wire endpiece (3, 11), said inner shaft (4, 14) having a first fiber A guidewire having a composite material, at least at the distal wire end (3, 11), the inner shaft (4, 14) having a plurality of weakening points (8, 18) generated by mechanical aggression. Is characterized in that the weakening points (8, 18) are generated by torsional loads, bending loads and/or breaking loads. Therefore, a method of manufacturing such a guide wire has been proposed for producing the weakening points (8, 18) by torsional, bending and/or breaking loads.
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