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INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS

机译:RAC1的抑制剂及其用于治疗癌症的用途

摘要

The present invention concerns a compound having the following formula (I): wherein: - A is in particular -N(R'a)-C(=O)-R, R'a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): - X is in particular chosen from the group consisting of: -SO2-N(R'b)-, R'b being H or a (C1-C6)alkyl group, -N(R"b)-SO2-, R"b being H or a (C1-C6)alkyl group, -CO-NH-, and -NH-CO-, for use for the treatment of cancers, such as metastatic cancers.
机译:本发明涉及具有下式(I)的化合物:其中: - a特别是-N(r' a ) - c(= O)-R,R' a 是h或a(c 1 -c 6 )烷基,并且R是具有下式(II)的基团: - x在特别选用由组成的组:-so 2 -n(r' b ) - ,r' b 是h或a(c 1 -c 6 )烷基,-n(r“ b ) - SO 2 - ,r” b 是h或a(c 1 -c 6 )烷基,-CO-NH-和-NH-CO-,用于用于治疗癌症,如转移性癌症。

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