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INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS

机译:RAC1的抑制剂及其在治疗癌症中的用途

摘要

The present invention concerns a compound having the following formula (I): wherein: - A is in particular -N(R' a )-C(=O)-R, R' a being H or a (C 1 -C 6 )alkyl group, and R being preferably a group having the following formula (II): - X is in particular chosen from the group consisting of: -SO 2 -N(R' b )-, R' b being H or a (C 1 -C 6 )alkyl group, -N(R" b )-SO 2 -, R" b being H or a (C 1 -C 6 )alkyl group, -CO-NH-, and -NH-CO-, for use for the treatment of cancers, such as metastatic cancers.
机译:本发明涉及具有下式(I)的化合物:其中:-A特别是-N(R'a)-C(= O)-R,R'a是H或(C 1 -C 6)烷基,并且R优选是具有下式(II)的基团):-X特别地选自:-SO 2 -N(R'b)-,R'b为H或(C 1 -C 6)烷基,-N(R“ b)-SO 2-,R” b为H或-(C 1 -C 6)烷基,-CO-NH-和-NH-CO-,用于治疗癌症,例如转移性癌症。

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