首页>
外国专利>
METHODS AND COMPOSITIONS FOR HOMOLOGY-DIRECTED REPAIR OF CAS ENDONUCLEASE MEDIATED DOUBLE STRAND BREAKS
METHODS AND COMPOSITIONS FOR HOMOLOGY-DIRECTED REPAIR OF CAS ENDONUCLEASE MEDIATED DOUBLE STRAND BREAKS
展开▼
机译:CAS内切核酸酶的同源定向修复的方法和组合物介导的双线断裂
展开▼
页面导航
摘要
著录项
相似文献
摘要
Compositions and methods are provided for effecting homology-directed repair at the site of a double-strand-break repair in a polynucleotide. In some aspects, the frequency of HDR is improved as compared to a control method. In some aspects, the ratio of HR to NHEJ is increased. In some aspects, the percentage of HR relative to the total number of mutant reads is increased.
展开▼