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MICROFLUIDIC DEVICE FOR SINGLE CELL PROCESSING AND METHOD AND SYSTEM FOR SINGLE CELL PROCESSING USING THE MICROFLUIDIC DEVICE
MICROFLUIDIC DEVICE FOR SINGLE CELL PROCESSING AND METHOD AND SYSTEM FOR SINGLE CELL PROCESSING USING THE MICROFLUIDIC DEVICE
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机译:用于单电池处理的微流体装置和用于使用微流体装置的单电池处理的方法和系统
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摘要
There is provided a microfluidic device for single cell processing including: a substrate; a fluidic channel provided in the substrate; and a plurality of electrodes arranged adjacent to the fluidic channel for determining a position of a cell in the fluidic channel, the plurality of electrodes comprising a pair of sensing electrodes comprising a first sensing electrode and a second sensing electrode, wherein at least the first sensing electrode of the pair of sensing electrodes extends in a first direction, the pair of sensing electrodes is configured to measure a differential electrical signal across a sensing region as the cell flows through the sensor portion of the fluidic channel; and a biasing electrode arranged between the first sensing electrode and the second sensing electrode, the biasing electrode being configured to receive a biasing voltage. One of the second sensing electrode and the biasing electrode extends in a direction at least substantially parallel to the first sensing electrode and the other one of the second sensing electrode and the biasing electrode is arranged to have a slanted orientation with respect to the first sensing electrode. There is also provided a method of forming the microfluidic device, and a method and a system for single cell processing using the microfluidic device.
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