Problem to be solved: to provide a water treatment substrate, a water treatment apparatus, a cooling tower, and a cooling system capable of continuously obtaining the effect of the water-soluble compound in the liquid state of the water-soluble compound in the liquid state while continuously reducing the number of the medicine and the replenishment frequency, and for the long term.Solution: cooling device 10 for cooling using cooling water, cooling tower 12 for cooling cooling water supplied from cooling device 10, and water treatment apparatus 1 for treating cooling water comprising water-soluble compound comprising resin material blended with water insoluble resin without being supported by inorganic support and 1 Cooling system 100 comprising 4 or cooling tower 12.Diagram
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