A procedure to propagate lero-2,2-defenil-4-dimethylamin-1-pentanal and its aquosoluble salts (Machine-translation by Google Translate, not legally binding)

摘要

A process for preparing the novel levo-2-diphenyl-4-dimethylamino-1-pentanal compound substantially free of the dextra-gyrate form comprising the treatment of a dextro2-2-diphenyl-4-dimethylamino pentanenitrile solution in an inert organic solvent with an intermediate amount between about one-quarter and one-half of lithium aluminum hydride per mole of nitrile under essentially anhydrous conditions and hydrolyzing the reaction mixture; and if so desired by converting levo-2-2-diphenyl-4-dimethylamino-1-pentanal to a water-soluble and non-toxic salt by the addition of a strong acid or a strong inorganic or organic acid ester. (Machine-translation by Google Translate, not legally binding)