process for preparing salts of pararosaniline with acid, 2,2 '- dihydroxy - 1,1' - (3,3 '- dicarboxylic dinaphtylmethane

摘要

Orally administrable therapeutic compositions in dosage unit form comprise a pharmaceutical carrier and, as active ingredient, pararosaniline or a salt thereof with a mineral acid or with a p monobasic organic acid containing a single carboxyl or sulphonic acid group. Suitable salts are the hydrochloride (parafusehin), hydrobromide, hydroiodide, acetate, sulphate, palmitate, stearate, salicylate, hydroxynaphthoate and 2-hydroxy-6-naphthalene sulphonate, the compositions preferably containing from 50 to 500 mg. of pararosaniline per dosage unit, e.g. as tablets, powders, capsules, solutions, suspensions and enterically coated forms comprising conventional solid and liquid carriers, diluents, preservatives and flavouring agents.