Procedure for obtaining hydrosoluble steroids derived from androstano. (Machine-translation by Google Translate, not legally binding)

摘要

PROCEDURE FOR OBTAINING HYDROSOLUBLE STEROIDS DERIVED FROM ANDROSTAÑO, whose general formula is represented in figure 1, where -R- is hydrogen or a lower alkyl group comprised between one and four carbon atoms or a venil or an ethynyl, and where -Z- is a free or esterified oxydril, such as 17-acetate, propionate, cyclopentylpropionate, esahydrobenzoate, succinate, trimethylacetate, heptylate, characterized by subjecting 11 β -hydroxy or 11 α -hydroxy Δ 4 -3-ketosteroids to reaction with formate of ethyl in benzene-pyridine and the 2-hydroxy-methylene derivatives are formed. Of these, by reaction with 2,3-dichloro-5,6-dicyan-benzoquinone in dioxane 2-formyl- Δ 1,4, -11 hydroxy steroids are prepared, either from the 11 β series or of the series 11 α. (Machine-translation by Google Translate, not legally binding)