A process for the preparation of tablets by compression of powder mixtures of pharmaceutical preparations without prior granulation.

摘要

Pharmaceutical tablets are made by mixing together powdered tablet ingredients (active compounds, fillers, diluents, &c.) and from 1 to 10% by weight of pulverulent polyethylene glycol, gelatin and/or polysaccharide (other than starch, modified starch and starch derivatives) and forming the mixture into tablets by compression without a prior granulation or moistening step. Examples relate to tablets comprising; (a) 2-methyl-3-o-tolyl-4(3H)-quinazolinone, (b) dimethylaminophenyldimethyl-pyrazolone, phenacetin and caffeine and, (c) meprobamate.