A procedure for preparing benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)

摘要

A process for preparing benzodiazepine derivatives, characterized by cyclizing a compound of the general formula **(See formula)** where X represents a carbonyl or methylene group; R1 represents hydrogen or lower alkyl; represents hydrogen, halogen lower alkyl, lower alkoxy or trifluoromethyl; R3 and R4 are the same or different and each represent hydrogen, lower alkyl, halogen, lower alkoxy, trifluoromethyl, nitro, lower alkylthio, lower alkylsulfinyl or lower alkylsulfonyl; and R5 and R6 represents hydrogen, lower alkyl, acyl, aryl, or lower aralkyl, or a respective halohydric salt, under acidic conditions, to produce a 5-phenyl-3H-l, 4-benzodiazepine derivative of the general formula **(See formula)** where X, R1, R2, R3 and R4 have the same meaning as indicated above. (Machine-translation by Google Translate, not legally binding)