METHOD OF PREPARING 3,9-BIS-(AMINOALKYL)-2,4,8,10-TETROXASPIRO {8 5,5{9 UNDECAN

摘要

1,209,994. Bis - (aminoalkyl) - tetraoxaspfro[5,5]undecanes. AJINOMOTO CO. Inc. 6 May, 1968 [12 May, 1967], No. 21258/68. Heading C2C. A 3,9 - bis - (aminoalkyl) - 2,4,8,10 - tetraoxaspiro[5,5]undecane of general formula where R is a straight or branched chain alkylene group of 2-10 C atoms is produced by the catalytic reduction of the corresponding nitrile of general formula wherein the hydrogenation is carried out in the molten state at elevated temperature in the presence of NH 3 and a Raney cobalt or nickel formate catalyst and in the absence of a solvent. In examples the 3,9-bis-(3-aminopropyl)-, -(1,1- dimethyl - 4 - aminobutyl) -, - (4 - aminobutyl)-, - (5 - aminopentyl) -, - (7 - aminoheptyl) - and - (11 - aminoundecyl) - 2,4,8,10 - tetraoxaspiro- [5,5] undecanes are prepared.