process for the production of radioactive quecksilberisotopen marked fluoresceinderivaten

摘要

1,220,499. Radio-active organo mercury compounds. CESKOSLOVENSKA AKADEMIE VED. 24 June, 1968 [12 July, 1967], No. 30085/68. Heading C2J. In the purification of radio-active mercury fluorescein compounds, for example those prepared as described in Specification 1,169,998, the reaction product is subjected to chromatographic separation on a column of alumina. Unreacted fluorescein derivatives and mercury compounds are eluted with water, difluoresceinyl mercury with bicarbonate solution, hydroxy-mercuri-fluoresceins with carbonate solution, and bis - (hydroxy - mercuri)- fluorescein compounds with sodium hydroxide solution. In examples the separation is described of difluoresceinyl mercury, mono- and bis-(hydroxymercuri) compounds of fluorescein, and the monohydroxymercuri-compounds of 2,7 - dibromo -, 4,5 - dibromo -, and 2,7 - diiodo-fluorescein; the mercury isotope may be Hg 197 or Hg 203.