首页>
外国专利>
Dihydroquinidine polyannuronate - antiarrhythmic - with reduced side-effects
Dihydroquinidine polyannuronate - antiarrhythmic - with reduced side-effects
展开▼
机译:二氢奎尼丁多环戊酸酯-抗心律失常-副作用减少
展开▼
页面导航
摘要
著录项
相似文献
摘要
Dihydroquinidine polymannuronate - antiarrhythmic, with reduced side-effects. Title cpd. which has the empirical formula: (C26H34O8N2)X (where x is the no. of monomeric mannuronic acid units in the poly-acid), possesses the antiarrhythmic activity of dihydroquinidine, but does not cause local irritation of the digestive tract and gives stable and long-lasting blood dihydroquinidine levels. It may be prepd. by reacting stoichiometric amounts of dihydroquinidine and polymannuronic acid, either in free form or as organic or inorganic salts, at 70-75 degrees C in the presence of a solvent until the pH of the soln. is practically 7, then isolating the salt formed.
展开▼