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membrane for an in vitro resorptionsmodell of gastrointestinaltrakte

机译:胃肠道体外吸收模型的膜

摘要

Membranes as in 1798340 for an in-vitro model of the gastrointestinal tract for simulating natural absorption processes have as lipoid component of the impregnating fluid a dioctylsodiumsulphoscuccinate; and pref. membranes are impregnated with a 97:3 mixture of lauryl alcohol and dioctylsodiumsulphonsuccinate. The test-solns. are circulated by a tubular pump through the two chambers of the diffusion vessel separated by the membrane which serves to maintain the pH-gradient between them and allows the differential passage of various medicaments - organic acids and bases of widely differing constitution.
机译:在1798340中,用于模拟自然吸收过程的胃肠道体外模型的膜,其浸渍液的脂质成分为二辛基磺基琥珀酸二辛酯。和偏好。膜用月桂醇和磺基琥珀酸二辛酯钠的97:3混合物浸渍。测试索恩斯。液体通过管式泵循环通过扩散容器的两个腔室,该两个腔室由膜分隔开,该膜用于保持它们之间的pH梯度,并允许各种药物(有机酸和组成广泛不同的碱)的差异通过。

著录项

  • 公开/公告号DE000002004236C

    专利类型

  • 公开/公告日1973-02-01

    原文格式PDF

  • 申请/专利权人 BOEHRINGER SOHN INGELHEIM;

    申请/专利号DE2004236A

  • 发明设计人 STRICKER HERBERT DR;

    申请日1970-01-30

  • 分类号G01N13/04;

  • 国家 DE

  • 入库时间 2022-08-23 07:09:03

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