Procedure for the obtaining of 1,2 - dihydro - pyrid (2,3 - d) pyrimidin - 2 - onas. (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for obtaining 1,2-dihydropyrido- [2,3-d] pyrimidin-2-one, of formula Ib, **(See formula)** where R means a hydrogen atom or an alkyl radical of 1 to 5 carbon atoms, means an alkyl radical of 1 to 6 carbon atoms, a cycloalkyl radical of 3 to 6 ring members, or the allyl, metalyl or propargyl radical, and R2 means the phenyl radical or a substituted phenyl radical of formula II, **(See formula)** wherein Y means a fluorine, chlorine or bromine atom, or an alkyl or alkoxy radical of 1 to carbon atoms, and Y1 means a hydrogen, fluorine, chlorine or bromine atom, or an alkyl or alkoxy radical of 1 to 4 carbon atoms, characterized in that a compound of formula Ia is reacted, **(See formula)** wherein R, R1 and R2 have the meanings indicated above, in an organic solvent that is inert under the reaction conditions, preferably with an alkali metal borohydride and at a temperature of 2O ° to 40ºC or also with lithium hydride -aluminum and at a temperature of 15º to 70ºC. (Machine-translation by Google Translate, not legally binding)